Abstract
Kikuchi-Fujimoto disease, or histiocytic necrotising lymphadenopathy of unknown aetiology, is a rare, benign and self-limiting cause of lymphadenopathy often involving the cervical nodes, and rarely presenting with mesenteric lymphadenopathy. We present a 26-year-old Caucasian male, who presented with right iliac fossa pain and low grade pyrexia, mimicking acute appendicitis. He underwent a laparatomy and an extended right hemi-colectomy for a caecal mass. Histology of the specimen showed lymph nodes with extensive areas of necrosis, with abnormal architecture suggesting Kikuchi-Fujimoto lymphadenopathy. This was further confirmed by immunohistochemistry. In this context maintenance of a high index of suspicion of this condition can avoid major surgical interventions. We describe the management of our case of Kikuchi-Fujimoto's disease involving the mesenteric nodes and provide an up to date review of the pertinent literature on this subject.
Highlights
Kikuchi-Fujimoto disease (KFD), known as JKUVKQE[VKE PGETQVK\KPI N[ORJCFGPKVKU YCU sTUV FGUETKDGF in Japan
We describe a case of KFD with presentation mimicking acute appendicitis and put forward an up to date review of literature relevant to the management of KFD
In 1972, Kikuchi and Fujimoto, independently, described necrotising cervical lymphadenitis with focal proliferation of reticular cells accompanied by numerous histiocytes and extensive nuclear debris
Summary
Anne Shrestha,[1] Katie Newton,[1] Emyr Benbow,[1] Rajeev Kushwaha1 1Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL
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