Ketogenic Diet with Severe Altered States of Consciousness in Children

Gregory Hansen

doi:10.31031/ntnf.2021.06.000628

Abstract

Ketogenic Diet with Severe Altered States of Consciousness in Children

Highlights

Recommendations for children with severe altered states of consciousness does not include ketogenic nutrition
Robertson et al [13] studied the effect of glucose administration after head injury and reported how it was the major cause of suppressed ketogenesis and may increase lactic acidosis
We recognized that a high protein ketogenic diet would be problematic with the conversion of glucogenic amino acids into glucose through gluconeogenesis, our mean protein provision remained poor at 0.58 g/kg/day

Summary

Introduction

Recommendations for children with severe altered states of consciousness does not include ketogenic nutrition. In brain injury animal models, ketones have demonstrated significant neuroprotective effects through improved mitochondrial metabolic efficiency, decreased oxidative stress, preventing metabolic deficits, attenuating apoptosis, and reducing excitotoxicity [2,3,4,5,6,7,8,9,10] In humans, their use has been suggested or trialed in a number of chronic neurologic conditions including Alzheimer’s disease, severe refractory epilepsy, intracranial neoplasms, Parkinson’s [11], and mitochondrial diseases [12]. The purpose of this study was to evaluate short-term quality control outcomes for a ketogenic diet in severe pediatric ACS, document challenges, and guide steps

Objectives

Discussion

Conclusion