Abstract

To date, ketamine is the only prescribable psychedelic medicine in the United States. Ketamine is also one of the most promising drugs for the treatment of depression. In the current paradigm of care, most ketamine clinics in the United States treat patients with mood disorders with ketamine and its derivatives alone without psychotherapy. The purpose of this article is to review the most recent literature about ketamine and psychotherapy for the treatment of psychiatric disorders and reflect and open a discussion about the potential benefits of combined ketamine treatment with psychotherapy versus ketamine alone. [ Psychiatr Ann. 2022;52(9):371–374.]

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