Abstract
By a series of observations some months ago I was led to the conclusion that the virus of herpes simplex when implanted on diseased skin may result in an eruption of greater severity and extent than the usual group of herpetic vesicles. My attention was first directed to this subject by observation of the eruption the course of which is here described. Case1.—M. L., 2½ years of age, had had atopic eczema for many months, present in a mild form in each cubital area as a papular eruption with occasional exudative manifestations. The course of the eruption changed suddenly, with no evident relation to environmental or dietary changes, when one arm suddenly presented increasing redness, swelling and a papular outbreak. The lesions soon became discrete tense vesicles of a size and tenseness greater than are usually observed in eczematous eruptions. Associated with the development of fever and
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