Neonatal liver transplantation for fulminant hepatitis caused by herpes simplex virus type 2.

Abstract

Neonatal herpes simplex virus (HSV) infection can cause skin disease or disseminated infection, resulting in hepatitis, pneumonitis, intravascular coagulopathy, or encephalitis (1). It is usually acquired perinatally, with a high mortality rate in disseminated disease (1–3). We describe a 12-day-old girl with fulminant hepatitis and fulminant hepatic failure (FHF) secondary to HSV type 2 infection who underwent a successful liver transplantation (LT).