Abstract
Corticosteroid therapy has revolutionized the treatment of many diseases in medicine. The most concerned diseases are chronic inflammatory diseases. Its use may be either short-term or long-term, thus generating several side effects, some of which are conventional and known, but others are rare, such as Kaposi’s sarcoma. We report here a particular clinical observation. Observation: This is a patient of 37 years, who consults in Internal Medicine for the treatment of mucocutaneous lesions, papular nodular, hyper pigmented, budding and disseminated appeared after six months of corticosteroid therapy. This treatment was introduced for the treatment of acoustic neurinoma. The patient is not diabetic or alcoholic and has a negative HIV status. The diagnosis of Kaposi’s sarcoma was made by histology of biopsied skin lesions which concluded for a regular proliferation without atypia spindle cell or mitosis. The lesions persisted over a month despite discontinuation of corticosteroid therapy. Treatment with Bleomycin was necessary. The outcome was favorable under treatment with progressive and complete disappearance of lesions after 15 treatments. Conclusion: The classical side effects of long-term corticosteroid are known, but Kaposi sarcoma complicating long-term corticosteroid is rare in the literature. It is vital that any long-term corticosteroid should be the subject of careful and regular monitoring.
Highlights
ObservationIt is a patient of 37 years old; he isaccounting officer, followed by throat specialist for a neurinoma
The anti-inflammatory properties of corticosteroids are used therapeutically since 1948, revolutionizing the treatment of many diseases [1]
We report the clinical observation of a Kaposi’s sarcoma-induced long-term corticosteroid in a patient without other factors of immune suppression
Summary
It is a patient of 37 years old; he isaccounting officer, followed by throat specialist for a neurinoma. After 6 months of treatment, had appeared gradually, painful swelling of the lower limbs, and secondarily mucocutaneous lesions, papular nodular hyper pigmented, budding and disseminated. What motivated his hospitalization in support for service. At the foot lymphangite associate in papulo nodular lesions, hyper pigmented, extending to the lower limbs. The left big toe is the site of kaposi’s lymphangit (Figure 1) These lesions extend to the palms (Figure 2), buttocks, and back. The paraclinical examination including histology of skin lesions biopsied concluded the diagnosis of Kaposi’s sarcoma showing the presence of a steady proliferation without atypia spindle cell or mitosis. The patient was reviewed two years after the cures and well
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