Abstract
ABSTRACTAimIn a previous unpublished study, we reported that Kampo therapy improved the prognosis of idiopathic interstitial pneumonia (IIP). KL‐6 is also associated with the inflammatory process of the alveolar unit, including type II epithelial cells. In this study, we measured KL‐6 as an index of the alveolar wall destruction in the progression of IIP.MethodsOf the 59 patients who initially participated in the previous study, KL‐6 was evaluated during the follow‐up period and compared with that at baseline in 18 patients.ResultsKL‐6 gradually decreased during the follow‐up period, although the difference was not significant on two‐way repeated measures ANOVA.ConclusionKampo therapy could be effective in improving the prognosis of IIP, partly due to inhibition of lung inflammation.
Published Version
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