Justification of the need for correction selenium status in the treatment of thyrotopathy among Ukrainians (review of literature and their own observations)

Abstract

The review analyzes the evidence base presented in scientific publications, which proves the importance of selenium for normal functioning of the thyroid gland. Presented data have connections with the involvement of selenium in the formation of thyroid hormones, their distribution in organs and systems, and peripheral metabolism. The role of the main selenoproteins participating in these processes is specified. The data of PubMed on the availability of selenium to residents of European countries is given, which is mainly estimated as suboptimal, but in a number of countries as insufficient. The author cited the results of her own studies of the level of selenium in the hair in certain groups of female patients and thyopathology, living in different regions of Ukraine. Based on the literature review and own observations, the author focuses on the relevance of the problem of selenium deficiency in Ukraine and on the need to expand research in this direction, because today there are opportunities with selenium-containing drugs to increase the effectiveness of prevention and treatment of various thypathology.