Abstract
Paratuberculosis (Johne's disease) occurs worldwide and is widespread in the United States. A slaughter survey in cows from northeastern states estimated the prevalence of paratuberculosis in cull dairy cows at 7.3% and a similar survey in Wisconsin revealed a 10.8% prevalence.
 Economic losses due to paratuberculosis may include decreased milk production, premature culling, and increased susceptibility to other diseases. In Pennsylvania alone, over 500 herds positive for Johne's disease have been identified with economic losses estimated at $5.8 million annually. Of the 10.8 million dairy cows in the U.S., nearly 1 million are thought to be affected, and the total losses due to paratuberculosis are expected to exceed $1.5 billion annually for the dairy industry in the United States.
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