Abstract
Controlling Johne's disease: vaccination is the way forward.
Highlights
M. avium subspecies paratuberculosis, hereafter referred to as MAP, is a significant veterinary pathogen that causes Johne’s disease in ruminants, including cattle, sheep, and goats
Transmission is by ingestion of the bacterium while grazing on pastures contaminated by this shedding process
A perfect example of the power of genomics was demonstrated a few years later when libraries of transposon mutants and transcriptomic studies were reported by several groups working with MAP (Shin et al, 2006; Wu et al, 2006, 2007; Janagama et al, 2010)
Summary
M. avium subspecies paratuberculosis, hereafter referred to as MAP, is a significant veterinary pathogen that causes Johne’s disease in ruminants, including cattle, sheep, and goats. To best combat this chronic infection, vaccination has the promise to reduce economic losses and control Johne’s disease. In the conception of this eBook for Frontiers in Cellular and Infection Microbiology, we solicited communications describing technologies and approaches to immunize animals against Johne’s disease.
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