Abstract
Johne’s disease is caused by Mycobacterium avium ssp. paratuberculosis (MAP) and can be a costly and frustrating disease in beef herds. Clinical Johne’s disease in cattle arises years after inoculation as diarrhea and progressive weight loss. Prior to reaching clinical status, subclinically infected cattle can shed bacteria into their environment, leading to continued spread of the disease within herds. The duration of subclinical infection is highly variable, and the humoral immune response and the amount of fecal shedding of MAP can vary greatly between individuals and throughout the year. Currently available diagnostic tests (serum ELISA, fecal PCR, fecal culture) each have significant limitations. Assays may differ in their utility depending on whether they are used to confirm clinical cases of Johne’s disease or to screen healthy cattle for potential infection.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: American Association of Bovine Practitioners Conference Proceedings
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
