Jerawat (Acne vulgaris): Review Penyakit Infeksi Pada Kulit

Abstract

The skin is a layer of tissue that spreads all over the body surface. On the surface of the skin, sweat glands secrete waste products through the pores of the skin in the form of sweat. Acne ( Acne vulgaris ) is a condition in which the pores become clogged and cause the pus pockets to become inflamed. The exact cause and pathogenesis of acne vulgaris are not clear. However, many factors are associated with the pathogenesis of acne, such as increased sebum secretion, hyperkeratosis of hair follicles and Propionibacterium acnes bacterial colonies, and inflammation and other factors, namely stress, climate/temperature/humidity, cosmetics, diet, and drugs. Acne vulgaris is provoked by Propionibacterium acnes in adolescence, under the influence of normal circulating dehydroepiandrosterone (DHEA). Acne formation mechanism ( Acne vulgaris ), namely stimulation of the sebaceous glands which causes excess sebum usually begins during puberty, abnormal keratinocyte proliferation, adhesions, and differentiation of lower branches of follicular follicles, and formation of inflammatory lesions that play a role in the Propionibacterium acnes bacteria. Acne treatment ( Acne vulgaris ) is carried out by repairing abnormal follicles, reducing sebum production, reducing the number of Propionibacterium acnes colonies or their metabolic products, and reducing inflammation of the skin.