Jejunal stromal tumor

Abstract

A 70-year-old man was referred because of intermittent anemia and lower abdominal pain. Barium contrast radiography of the small intestine revealed a 5 × 4-cm filling defect about 20 to 30 cm distal to the ligament of Treitz (A). Push enteroscopy disclosed a firm nodular mass. There were deep ulcerations but otherwise the mass was covered by normal-appearing mucosa (B). Biopsy specimens revealed a proliferation of spindle cells. Immunohistochemical staining was positive for c-kit, but negative for smooth muscle actin (SMA), S-100, and CD34, findings compatible with a diagnosis of a GI stromal tumor.