Abstract
Twelve isolates of Streptomyces spp. from tobacco soils were screened for the production of antibiotics, of which two were found to be efficient. Growth pattern of the two potential isolates was studied and their antimicrobial activity was tested against Aspergillus flavus, A. niger, Pythium aphanidermatum, Bacillus subtilis and Pseudomonas fluorescens . Isolate 2 was found to be more effective and caused maximum inhibitory zone of 108 mm after 120 hrs against P. aphanidermatum . The area of the inhibitory zone observed in both the isolates was directly proportional to the age of the culture for up to 120h.
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