ISOLATION OF MIRICETINE-CONTAINING FRACTIONS FROM LINOSYRIS VILLOSA PLANT AND THEIR APPLICATION AS ANTIANEMIC AGENT

Abstract

With the development of chemistry, natural substances were actively supplanted from human life by chemical products. However, despite the enormous progress in this area, in recent decades, the problems of serious side effects of synthetic chemicals on the environment have become more and more pronounced. Methods of two-dimensional and one-dimensional paper chromatography, column adsorption chromatography, gas chromatography, and IR spectroscopy were used. The purpose of the article is to study the chemical composition of the Linosyris villosa plant by physicochemical methods of analysis. Creation of dosage forms based on it. The problem of the article is the search and creation of drugs based on the flora of Northern Kazakhstan. The scientific novelty lies in the fact that the chemical composition and biological activity of the Linosyris villosa plant, growing in the territory of Northern Kazakhstan, is being studied for the first time. According to the results of the analysis, in 13% of patients the treatment effect is insignificant, and in 87% of patients there was an improvement in blood values (increase in hemoglobin, an increase in the number of red blood cells, almost all patients returned color index of blood), the number of white blood cells increased to normal, and the WBC differential improved. Therefore, the drug “Vitin”, an aqueous-alcoholic extract of the Linosyris villosa, is an effective drug for the treatment of patients with anemia of varying severity. The practical significance of the work is defined as follows: biologically active compounds from the Linosyris villosa plant were obtained for the purpose of studying and applying them in medicine and agriculture.