Isolation of Bioactive Marker Component, Butyryl Alkannin from Arnebia euchroma Roots and Its Efficacy Against Multidrug-Resistant Pathogens

Abstract

This study was carried out to investigate the biomedicinal efficacy of a bioactive marker component, butyryl alkannin isolated from n-hexane root extract of Arnebia euchroma against vancomycin-intermediate Staphylococcus aureus (VISA) and methicillin-resistant S. aureus (MRSA) pathogens. As a result, butyryl alkannin showed significant antibacterial activity against multidrug-resistant pathogens of VISA and MRSA as minimum inhibitory concentration values which were found to be 1.56 and 1.56 μg/ml, respectively. These findings justify the biomedicinal efficacy of butyryl alkannin compound.