Abstract
<p class="Abstract"><i>Bifidobacterium</i> is a group of Lactic Acid Bacteria (LAB) that commonly found in the gastrointestinal tract and vagina. LAB has many health benefits, such as produce an antimicrobial substance against a pathogen. This research aims to isolate <i>Bifidobacterium</i> from an infant’s feces and know its antimicrobial activity against <i>Escherichia coli</i> and <i>Candida albicans.</i> A total of 5 isolates <i>Bifidobacterium</i> spp. were isolated from the sample. <span lang="EN">The largest inhibitory activity against <i>E. coli</i> was shown by isolate Bb3F, with the inhibitory zone of 10.80 mm. While the largest inhibition activity against <i>C. albicans</i> was shown by isolate Bb1B and Bb3F with the inhibitory zone of 9.70 mm.</span><o:p></o:p></p>
Highlights
Bifidobacterium is a Gram-positive bacterium, anaerobic, hetero-fermentative, non-spores-forming, nonmotile and included in Lactic Acid Bacteria [1]
Many Bifidobacterium is recognized as probiotics where probiotics are living bacteria that give some health benefits to the host when administrated in a sufficient amount and have wider applications in food, feed, dairy and fermentation industry as non-pharmacological approaches for health management [2,3]
The largest inhibitory activity against E. coli was shown by isolate Bb3F, with the inhibitory zone of 10.80 mm, while the smallest inhibition was shown by isolate Bb1G i.e. 6.0 mm
Summary
Bifidobacterium is a Gram-positive bacterium, anaerobic, hetero-fermentative, non-spores-forming, nonmotile and included in Lactic Acid Bacteria [1]. Bifidobacterium commonly found in the human digestive tract and vagina [4]. These bacteria can be found in the digestive tract of newborns [5]. Bifidobacterium is the dominant bacterium that lives in the digestive organs of newborns and the number decreases with age. The competition of microorganism attachment to intestinal epithelial cells is affected by exopolysaccharide production. Bifidobacterium produces some antimicrobial substances, such as hydrogen peroxide, organic acids, and bacteriocin. Bacteriocin is able to inhibit bacterial growth from the same species (narrow spectrum) or different genera (broad-spectrum), e.g. Listeria monocytogenes, Escherichia coli and Salmonella sp. [8]
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