Abstract
Apparently identical herpes-like viruses were isolated from the leukocytes of two lymphosarcomatous cows. The isolates caused syncytial formation in bovine embryonic spleen cell cultures but were structurally and antigenically unrelated to a bovine syncytial virus previously isolated and described byMalmquist et al. (11). Inoculation of the isolates into guinea pigs, rabbits, mice, hamsters and calves failed to reveal any evidence of pathogenicity but the virus was reisolated from three inoculated calves. The isolates were antigenically distinct from infectious bovine rhinotracheitis virus and pseudorabies virus. Neither their relationship to bovine herpes mammillitis virus nor their possible role in the etiology of bovine lymphosarcoma has been ascertained.
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