Abstract
Post-fermented Pu-erh tea (PFPT) has several health benefits, however, little is known about the bioactive compounds. In this study, a PFPT compound was isolated by column chromatography and identified as Teadenol A by spectroscopic data analyses, including mass spectrometry and 1D and 2D NMR spectroscopy. Teadenol A in tea leaves was biotransformed by Aspergillus niger and A. tamari at 28 °C for 14 d at concentrations ranging from 9.85 ± 1.17 to 12.93 ± 0.38 mg/g. Additionally, the compound was detected in 22 commercial PFPTs at concentrations ranging from 0.17 ± 0.1 to 8.15 ± 0.1 mg/g. Teadenol A promoted the secretion of adiponectin and inhibited the expression of protein tyrosine phosphatase-1B. Antioxidant assays (e.g., 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity, total antioxidant capacity (T-AOC), hydrogen donating ability, and superoxide anion radical scavenging capacity) revealed that Teadenol A has antioxidant properties. Therefore, Teadenol A is an important bio-active component of PFPT.
Highlights
Pu-erh tea (PET) is a traditional Chinese tea produced from sun-dried leaves of Camellia sinensis (Linn.) var. assamica (Masters Kitamura) in Yunnan, China
Compound 1 was isolated from the extract using column chromatography followed by purity analysis by HPLC
Compound 1 consisted of a white powder with a molecular ion peak at m/z 276.0638, which corresponded to the molecular formula C14 H12 O6 (Figure 3)
Summary
Pu-erh tea (PET) is a traditional Chinese tea produced from sun-dried leaves of Camellia sinensis (Linn.) var. assamica (Masters Kitamura) in Yunnan, China. Clinical studies have shown that the daily consumption of PFPT properties [11], with retrogressive effects on immunosenescence [12]. Have anti-obesity/hypolipidemic effects and regulate theabrownin (TB) [17,18], gallic acid (GA) [19], and statin [20] have anti‐obesity/hypolipidemic lipid (CAF) [21]Caffeine and polysaccharides [22,23]. CAF and catechins), and levels of polyphenols theaflavin, thearubigin, these(e.g., components are generally present in other teas(catechins,. (e.g., CAF and catechins), andmyricetin, levels of quercetin, kaempferol, and flavonol glycosides), amino acids, and soluble sugars decrease during. Fungi responsible for the biosynthesis of this compound its antioxidant activity in vitro.
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