Abstract
Peperomia pellucida is a member of the Piperaceae family. Extraction of plant material was carried out by Soxhlet extraction method using hexane and ethylacetate as solvents respectively. The extract was concentrated using a rotary evaporator, followed by isolation and purification using column and thin layer chromatographic techniques. Fraction C20 showed a clearly defined single spot with Rf value of 0.51. Using 1HNMR, 13C-DEPT, COSY, HSQC and HMBC and by comparison with literature values, the structure of the compound was established as an Ursane-type triterpenoid. The use of P. pellucida in ethnomedicine for the treatment of various ailments could be attributed to the Ursane-type triterpenoid and other bioactive chemical compounds present in the plant.
 Keywords: Peperomia pellucida, extraction, isolation, chromatographic techniques, ursane-type triterpenoid
Highlights
The use of medicinal plants in the treatment and management of various ailments has increased significantly such that a greater number of people in Nigeria rely on plant based medicines as their source of primary healthcare especially, in rural communities, (Karunamoorthi et al, 2013)
Peperomia pellucida is a member of the Piperaceae family
We report the isolation and NMR characterization of an ursane-type triterpenoid from the leaves of P. pellucida
Summary
Peperomia pellucida is a member of the Piperaceae family. Extraction of plant material was carried out by Soxhlet extraction method using hexane and ethylacetate as solvents respectively. P. pellucida is one of the known medicinal plants used in various parts of the world for the treatment of various diseases and infections such as rheumatism, diarrhea, dysentery, convulsion, epilepsy, paralysis, tumour, joint and abdominal pain, cough, cold, fever, asthma, boils, acne, renal disorders, fatique, headache, wound, vaginal and kidney infections (Coe and Anderson, 1999; Khan and Omoloso, (2002). We report the isolation and NMR characterization of an ursane-type triterpenoid from the leaves of P. pellucida.
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