Abstract
1. 1. Two perchloric acid-soluble glycoprotein fractions from cyst fluids of 2 patients with ovarian clear cell carcinoma in malignant were subjected to a systematic affinity chromatography using Vicia unijuga lectin-Cellulofine column and Arachis hypogaea lectin-Cellulofine column and separated into four glycoproteins, blood group N antigen precursor glycoprotein with Thomsen-Friedenreich (T) activity, N antigen precursor glycoprotein, T-active glycoprotein and serologically inactive glycoprotein, respectively. 2. 2. These serologically active glycoproteins isolated in yields of 0.3 ~ 3.3% of PASFs, were proved to be mucin-type glycoproteins with M w., of 509,000 ~ 2,772,000 Da and contained 33.9 ~ 81.7% carbohydrates.
Published Version
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