Abstract
Our aims are the prevalence and the pathophysiological approach of isolate hypothyroxinemia in pregnant women in the first quarter. Patients and methods Prospective study, on 270 pregnant women in the first trimester. Women with disrupted thyroid balance, who smoke (active smoking confessed) and those followed for thyroid disease or taking medications that interfere with the thyroid gland were excluded. Study protocol: clinical examination, urinary iodine, thyroid stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), thyroid antibodies (peroxidase antibody and thyroglobulin antibody). Statistics tests: collection of data on EPI INFO 5.1. Results 22/270 pregnant women in the first trimester (8.1%) had a hypo-thyroxinemia which 21/22 had benefited from a determination of iodide. – 06/21 cases (28.6%) had an inadequate iodine intake (ioduria – 09/21 cases (42.9%) had correct urinary iodine (ioduria between 150 and 250 μg/L). – 06/21 cases (28.6%) had a more than adequate iodine intake (ioduria ≥ 250 μg/L). Discussion Although the patho-physiological mechanisms of isolate hypo-thyroxinemia during pregnancy are not well understood, the knowledge of the disease is nevertheless appropriate.
Published Version
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