Is There a Role for an Evolutionary Genetics Based Rational Health Policy In Global Biomedical, Health and Economic Policies?

Abstract

The Biomedical Sciences Community has placed an exclusive emphasis on retrospective intervention(s) in managing pathological consequences, in thousands of diseases which cost hundreds of trillions of dollars per annum. In the treatment of some intractable and ghastly diseases, which are far more dehumanizing than any Death Camp, such as cancers and neurodegeneration(s) these approaches are largely ineffective. These diseases can only be successfully treated by preemption! Breaking the cycle perpetuating this paradigm and prospectively preempting disease causing mutations that escape the networks of genes maintaining chromosome and genome biology in mammalian development and homeostasis requires a combinatorial approach including complementary contemporary and classical methods with the recruitment of an evolutionary genetics approach for systematizing and controlling this network. This enterprise is predicated on a trans generational and international commitment through a framework of Institute(s) of Functional Mammalian Chromosome And Genome Biology funded by a variation of President Barack Obama’s budgetary rescue of the Detroit Motor Industry. The need is fulfilled by training, more and not fewer Ph.D. scientists with some re-directed to this goal, whose contributions will gradually diminish rates of disease allowing the re-allocation of hundreds of trillions of dollars spent each year from perpetuating the management of consequences of diseases to productive applications in Global Health and Economic Policy. The time scales for realization of these benefits of necessity, must be measured against the scale of many current ineffective therapies, and extended into perpetuity. Although based on other similar enterprises, returns on investment are likely to be accelerated once critical thresholds of data and knowledge are attained. As in anything meaningful that has ever been achieved in civilization, e.g. exploration of Space these commitments must be enduring. And so if humans never launched a Sputnik they could never build a Space Station!