Is There a Relationship between Serum D-Dimer Levels and Thorax CT Severity Score in Patients with COVID-19?: A Retrospective Analysis

Cevik Belma,Akın Kayıhan

doi:10.23937/2572-3235.1510089

Abstract

In this retrospective study, 84 patients with COVID-19 pneumonia who were diagnosed with RT-PCR and thorax CT findings and whose serum CRP and D-dimer levels were available were included. The study was performed in Lokman Hekim University between April 1, 2020 and December 31, 2020. The study was approved by the local ethics committee.

Highlights

The COVID-19 pandemic began in Wuhan (Hubei, China) in December 2019 and rapidly spread around the World
We investigated the relationship between D-dimer levels and thorax CT severity score in the patients with COVID-19
84 patients with COVID-19 pneumonia who were diagnosed with RTPCR and thorax CT findings and whose serum CRP and D-dimer levels were available were included

Summary

Introduction

The COVID-19 pandemic began in Wuhan (Hubei, China) in December 2019 and rapidly spread around the World. Because of RT-PCR sensitivity limitations [1], the radiology literature has focused on detecting the probability of infection of non-contrast CT findings [2]. The elevated serum D-dimer levels and its relationship with poor outcomes in COVID-19 pneumonia patients have been demonstrated [3]. D-dimer is known as a biomarker of inflammation. We considered that serum D-dimer levels may predict the severity of inflammation. CT involvement extent is the most visual parameter, which could reflect the severity of inflammation. We investigated the relationship between D-dimer levels and thorax CT severity score in the patients with COVID-19

Methods

Results

Conclusion