Abstract
Is there a Histopathologic Correlation of Prostatic PI-RADS Score 3 Lesions in Transition Zone in MRI with the Dynamic Contrast Curve Type? A Retrospective Single-Center Study
Highlights
Prostate cancer is the most frequent cancer type in males, but only about 20-30% of prostatic cancer originate in the transition zone (TZ)
The diagnosis is based on the prostate-specific antigen (PSA) screening in males over 40 years and transrectal or transperineal ultrasoundguided prostate biopsy
DCEP MRI can be useful in combination with T2 Sequences and DWI Imaging in the characterization of focal prostatic lesions in the peripheric (PZ) and in the transition zone (TZ)
Summary
Prostate cancer is the most frequent cancer type in males, but only about 20-30% of prostatic cancer originate in the TZ. The diagnosis is based on the prostate-specific antigen (PSA) screening in males over 40 years and transrectal or transperineal ultrasoundguided prostate biopsy. Prostate multiparametric MRI is indicated in patients with increasing PSA values (over 2, 5-3 ng/ml) and negative prostate biopsies and in patients with suspected trans-rectal palpation results. Multiparametric-magnetic resonance imaging (mpMRI) is indicated in localization and staging of clinically significant prostate cancer. DCEP MRI can be useful in combination with T2 Sequences and DWI Imaging in the characterization of focal prostatic lesions in the peripheric (PZ) and in the transition zone (TZ). Enhancement alone is not definitive for clinically significant prostate cancer, and absence of early enhancement does not exclude the possibility [2]
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