Is Reversal of Type 2 Diabetes Mellitus Possible? An Approach to Mitigate

Abstract

Diabetes mellitus defined as progressive and irreversible disease characterized by hyperglycaemia. It falls under top 5 cause of death and can led to series of diseases affecting vital organs. Type 1 diabetes is heredity disorder which leads to insufficiency of insulin in the blood. Type 2 diabetes mellitus is lifestyle dependent and occurs in later stages of life due to overweight. Excessive fat deposition in liver and pancreas leads to desensitization of receptors for insulin which leads to rise in blood glucose level. Type 2 diabetes mellitus is now known to be reversible with loss in body weight. Three methods of losing body weight are bariatric surgery, calorie restricted diet and carbohydrate restricted diet. All these methods help in reducing body fat which increases the insulin sensitivity and reduces blood glucose. Out of the three methods, carbohydrate restricted diet is proven to be most efficient.