Abstract
Methods Seventeen patients (8 M, 9 F, 25 ± 9 years) who underwent multiple transfusions for a chronic hematopathy (12 thalassemia major, 4 aplastic anemias, 1 sickle cell anemia), but who did not have any overt cardiac disease, and 2 normal volunteers underwent MR assessment of T2* times using a multi-echo gradient echo sequence to estimate iron content in the liver and heart. These parameters were correlated to LV volumes and ejection fraction measured using SSFP and regional circumferential shortening strain, and apical rotation and twist measured using tagged images with HARP analysis.
Highlights
Abstracts of the 13th Annual SCMR Scientific Sessions - 2010 Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-info
Recent studies have demonstrated the ability of T2* MR to measure cardiac iron concentrations in patients with multiple blood transfusions
We sought to evaluate whether cardiac iron overload is related to subclinical alterations of systolic left ventricular (LV) dysfunction in such patients
Summary
Address: Cliniques St. Luc UCL, Brussels, Belgium * Corresponding author from 13th Annual SCMR Scientific Sessions Phoenix, AZ, USA. Published: 21 January 2010 Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):P273 doi:10.1186/1532-429X-12-S1-P273. Abstracts of the 13th Annual SCMR Scientific Sessions - 2010 Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-info
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