Ion partitioning effect on the electrophoresis of a soft particle with hydrophobic core.

Abstract

A theoretical study on the electrophoresis of a soft particle made up of a charged hydrophobic inner core surrounded by polyelectrolyte layer (PEL) is made. The dielectric permittivity of the PEL and aqueous solution are considered to be different, which creates the ion partitioning effect. The ion partitioning effect, which is accounted by the Born energy difference, modifies the distribution of mobile ions in the PEL and hence alters the particle electrophoresis. The combined effects of core hydrophobicity and the ion partitioning effect on the mobility are determined based on the Debye-Huckel approximation under a thin Debye layer assumption. An analytic expression for the electrophoretic mobility taking into account the core hydrophobicity and ion partitioning effect is obtained. The occurrence of zero mobility and reversal of mobility of the soft particle is illustrated.