Abstract
Increasing concentrations of iodide in the medium produce a rise in the 127I newly bound to iodocompounds in the resting and phagocytosing human leukocytes. Organic iodine rises in resting leukocytes as the iodide concentration in the medium is increased from 0.001 to sol10 mg iodide 100 ml . There is no additional increase in organic iodine in phagocytosing leukocytes between 0.1 and sol10 mg iodide 100 ml ; however, the organic iodine is not significantly lowered at the highest iodide concentration in the media. These data prove that the Wolff-Chaikoff phenomenon is not demonstrable in human leukocytes.
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