Involvement of the central nervous system in vibration syndrome.

Abstract

In order to clarify the involvement of the central nervous system (CNS) in vibration syndrome (VS), patients with VS and age-matched controls were given a questionnaire and neurophysiological tests on auditory brainstem response (ABR), event-related potential (P300), short-latency somatosensory evoked potentials (SLSEP), and blink reflex (BR). Twenty-eight patients with a mean age of 56.3 (SD = 3.01, range 48-65) years from western Japan were examined. They had been on sick leave for an average of 6.13 (SD = 3.2, range 1-13) years at the time of the testing. Almost all were experiencing Raynaud's phenomenon in the winter of 1990-1991. They were not suffering from diseases or injuries which might have affected the CNS function. These patients were divided into two subgroups, one with more symptoms related to the CNS, especially memory and judgment (n = 13, group A), and the other with fewer symptoms (n = 15, group B). Normal controls with an average age of 55.8 (SD = 4.8, 48-65) years were people from the same area who met similar criteria. The ABR parameters of the patients were slightly, but not significantly, delayed compared with those of the controls. The SLSEP and BR parameters of the patients were not delayed. The latencies of P300 in group A were significantly delayed compared with those in the controls. The findings suggest that VS involves the cognitive and attention functions of the cerebral higher function, but not the conduction function in the auditory and somatosensory ascending tract and facial nerve reflex tract in the brainstem.