Abstract
Background: Impairment of the ability to adapt to stress in animals may contribute to some stress-related psychiatric disorders, such as anxiety and depression. A growing body of evidence has suggested that the brain’s serotonin (5-HT) nervous system may play an important role in the etiology, expression and treatment of anxiety and depression. The aim of the present study was to examine whether brain 5-HT7 receptors are involved in the formation of stress adaptation.
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