Abstract
Abstract Progesterone and synthetic steroids (RU-5020, progestomimetic; RU-38486, anti-progesterone and anti-glucocorticoid) inhibit glucose netabolism in female rat adipocytes. The inhibitory effect, which is dose-related, occured after 20-min of incubation and is sustained during 2-hours of incubation. This effect of progesterone is similar to that observed during pregnancy and after treatment of ovariectomized rats with progesterone (5 mg/rat/day-15 days).
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