Abstract
Saraca asoca Roxb. De Wilde - Ashoka is a Sanskrit word which means without sorrow or that gives no grief. Ashoka tree, universally known by its binomial Latin name Saraca asoca (Roxb.),De wild or Saraca indica belonging family Caesalpinacea. It is a small evergreen tree 7-10cm high. It occurs up to the altitude 750m. The plant is found to have spasmogenic, oxytocic, uterotonic, antibacterial, anti-implantation, antitumor, antiprogestational, antioestrogenic activity. The objective of this study is to evaluate the invitro cytotoxicity of the crude methanolic bark extracts of Saraca indica on HeLa cell lines using MTT assay. The extract possessed highly significant percentage of inhibition on the cell lines and the IC50 value was determined to be 14.63µg/ml. These results show a significant antitumor and cytotoxic effect of extract against human cervical cancer HeLa cell line and support the ethnomedical use of Saraca indica.
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