INVIROMENTAL FACTORS IN THE CONTEXT OF INFLAMMATORY BOWEL DISEASE (REVIEW)

Abstract

Inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, are characterized by a chronic recurrent course. With no established etiology, воспалительных заболеваний кишечника is considered as a multifactorial disease, affecting psychological and social well-being and significantly impairing the quality of life of patients. The burden of inflammatory bowel disease is increasing worldwide, with incidence rates and trends varying significantly between countries and regions. Changing trends in the epidemiology of inflammatory bowel disease are occurring in parallel with industrialization and significant invairomental changes associated with the westernization of society, confirming the role of non-genetic risks in the etiopathogenesis of inflammatory bowel disease. A combination of factors, including the improved socioeconomic status of newly industrialized countries initiating invairomental dynamics, increases the risk of inflammatory bowel disease. The impact of invairomental factors is a possible missing link in understanding the etiology and increasing prevalence of inflammatory bowel disease in recent years. Studying the relationship between environmental factors and inflammatory bowel disease may improve the understanding of etiopathogenesis, identify strategies for prognosis and prevention, and prepare health care systems for the growing burden of inflammatory bowel disease.