Abstract
In the present research paper, two systems based on Ti-Nb-Zr-Ta and Ti-Nb-Zr–Fe, containing non-toxic elements, are considered and investigated. The first aim of the paper is to enlarge up-to-date developed β-type Ti alloys, analyzing three different compositions, Ti-10Nb-10Zr-5Ta, Ti-20Nb-20Zr-4Ta and Ti-29.3Nb-13.6Zr-1.9Fe, in order to assess their further employment in biomedical applications. To achieve this, structural, microstructural, compositional and mechanical investigations were performed as part of this study. Based on the results obtained, the alloy with the highest Nb content seems to be the most appropriate candidate for advanced biomedical applications and, in particular, for bone substitution.
Highlights
Research in the field of metallic biomaterials has focused on the development of new, improved and safe metallic biomaterials, with high biological and mechanical biocompatibility, in order to avoid any harmful effects from elements such as V and Al, which are usually present in a commercially available alloy (TiAl6V4 alloy) [1,2,3]
In the present research paper, two systems based on Ti-Nb-Zr-Ta and Ti-Nb-Zr–Fe, containing non-toxic elements, are considered and investigated
In the present research paper, two systems based on Ti-Nb-Zr-Ta and Ti-Nb-Zr-Fe, made up of non-toxic elements, were chosen, in order to contribute to the enrichment of up-to-date and developed β-type Ti alloys for biomedical applications
Summary
Research in the field of metallic biomaterials has focused on the development of new, improved and safe metallic biomaterials, with high biological and mechanical biocompatibility, in order to avoid any harmful effects from elements such as V and Al, which are usually present in a commercially available alloy (TiAl6V4 alloy) [1,2,3] Even if their surface is functionalized, with different layers having high biocompatibility and bioactivity, there is a risk of hazardous effects on the human body caused by the toxic elements contained, if, over time, corrosion due to biological fluid ends up transferring ions from the implant material. The main areas of interest in the current research on biomaterials are focused on the development of biomaterials with composite structures and multilayer or surface-functionalized structures with micro- and nano-layers, in order to achieve good biocompatibility, acceleration of the osseointegration of the implant in the patient’s body and prevention of post-implant infections, as well as direct surface manipulation [9,10,11,12]
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