Investigation on Toxoplasma infection among patients with infertility in Chengde, Hebei Province

Abstract

Objective To investigate Toxoplasma infection in patients with infertility and its influencing factors in Chengde,Hebei Province.Methods The Toxoplasma antibody detection by enzyme linked immunosorbent assay (ELISA) was carried out in infertility patients who were consulting in Hospital of Chengde City between March 2012 to February 2014,at the same time,the infection history was traced in the positive cases of infection in patients with infertility.The data were analyzed using SPSS13.0 statistics software.Results 118 cases were Toxoplasma antibody positive in 1 474 cases (737 pairs) of patients with infertility,and positive rate was 8.01％(118/1474) while 19 cases positive in control group with the positive rate of 2.72％ (19/698),the difference was statistically significant (x2=22.37,P＜0.01).Seventy four cases were positive in male patients with infertility with the rate of 10.04％(74/737) while 44 cases were positive in female with the rate of 5.97％ (44/737).In the control group,11 cases were positive in male patients with infertility,the rate was 3.15％(11/349) while 8 cases were positive in female and the rate was 2.29％(8/349),the difference was statistically significant (P＜0.01).In 118 positive cases of infertility group,35 cases had a cat or a dog in their family,accounted for 29.66％(35/118); 54 cases often ate out,accounted for 45.76％(54/118); 31 cases were fond of eating hot pot or barbecue,accounted for 26.27％(31/118).In 1 356 negative cases of infertility group,97 cases had a cat or a dog in their family,accounted for 7.15％(97/1 356); 132 cases often ate out,accounted for 9.73％(132/1 356); 109 cases were fond of eating hot pot or barbecue,accounted for 8.04％(109/1 356).Conclusion The Toxoplasma infection rate is higher among infertility patients in Chengde,Hebei Province. Key words: Toxoplasma; Infertility; Infection rate; Influencing factor