Abstract
In present communication we report experimental density and speed of sound data for the antihypertensive drug Hydralazine hydrochloride in water and 0.05 mol.kg−1 L-alanine and L-valine aqueous solutions at temperatures 293.15, 298.15, 303.15, 308.15 and 313.15 K within the molality range of 0.06–0.15 mol.kg−1. By using the experimental density and speed of sound data and appropriate equations, we calculate the parameter like apparent molar volume of solute(Vϕ), limiting apparent molar volume of solute (Vϕ0), apparent molar expansivity(Eϕ), isobaric expansivity coefficient (α), limiting apparent molar expansivity(Eϕ0), isentropic compressibility(Ks), apparent molar isentropic compressibility of solute(KS, ϕ) apparent molar isentropic compressibility at the infinite dilutions(KS, ϕ0), and hydration number(nh). The limiting apparent molar volume of solute has been used to obtain transfer parameter for Hydralazine hydrochloride. The hydration behavior for the experimental studied drug in the different mediums has been understood by computing the hydration number.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
