Abstract
Objectivethis work was to investigate the impact of magnetic resonance imaging (MRI)-assisted surgery on immune cell factors and surgical efficacy in glioma patients, aiming to deepen understanding of surgical effects on immune status and provide evidence for clinical strategies. Materials and Methodsa retrospective analysis of 120 patients treated at Qianjiang Hospital from January 2022 to December 2023 was conducted. Patients underwent traditional craniotomy (control group, CG) or MRI-assisted stereotactic minimally invasive surgery (research group, RG). Immune cell factors, treatment outcomes, cognitive function, daily activities, and adverse reactions (ARs) were compared. Resultspostoperatively, arginine vasopressin (AVP) and β-endorphin (β-EP) levels decreased in both groups, more so in CG (P<0.05). Helper T cell 1 (Th1) levels increased in both, more in controls, while Th2 and Th17 decreased, more in CG (P<0.05). Glasgow coma scale (GCS) scores increased more in the RG, National Institutes of Health Stroke Scale (NIHSS) scores decreased more (P<0.05), and activities of daily living (ADL) scores increased more in the RG (P<0.05). The RG had more effective treatments and fewer ineffective outcomes (P<0.05), and fewer recurrences, metastases, and ARs (P<0.05). ConclusionMRI-assisted surgery enhances immune factors, functional abilities, and shows efficacy with fewer ARs, indicating its clinical value.
Published Version
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