Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir

Abstract

As a result of the intensive use of biotechnology in cattle breeding, the incidence of rare genetic defects in the population has started to increase. Studies have focused on identifying cattle with genetic defects using molecular methods. Identifying carrier cattle is crucial to reducing genetic defects in future generations. In a previous study conducted in Turkiye, Brachyspina Syndrome (BS) and Cholesterol Deficiency (CD) were detected in Holstein cattle. With regard to these two genetic defects, in the study conducted to investigate samples were taken from the Holstein cattle reared in Eskişehir by using PCR technique. 2 and 11 cattle were found to be carriers of the BS and CD, respectively, among 112 Holstein cattle. The possibility of the spread of genetic defects and economic damage can be prevented using molecular techniques. Some molecular methods can be used to detect genetic diseases. In this way, herds free of genetic defects can be produced.