Abstract
Structural proteins play critical roles in the food quality, especially texture properties, of sea cucumbers and their products. Most of the previous studies on sea cucumbers focused on few individual proteins, which limited our understanding of how structural proteins influenced the quality of sea cucumbers. Inspired by the clarification of sea cucumber (Apostichopus japonicus) genome, we established an integrated data of structural proteins in the sea cucumber body wall. A portfolio of 2018 structural proteins was screened out from the sea cucumber annotated proteome by bioinformatics analysis. The portfolio was divided into three divisions, including extracellular matrix proteins, muscle proteins, and proteases, and further classified into 18 categories. The presence of 472 proteins in the sea cucumber body wall was confirmed by using a proteomics approach. Moreover, comparative proteomics analysis revealed the spatial distribution heterogeneity of structural proteins in the sea cucumber body wall at a molecular scale. This study suggested that future researches on sea cucumbers could be performed from an integrated perspective, which would reshape the component map of sea cucumber and provide novel insights into the understanding of how the food quality of sea cucumber was determined on a molecular level.
Highlights
Structural proteins play critical roles in the food quality, especially texture properties, of sea cucumbers and their products
We suggested classifying the structural proteins of the sea cucumber into three divisions, including extracellular matrix (ECM) proteins, muscle proteins, and proteases (Table 1)
ECM glycoproteins are associated with collagens and proteoglycans to construct the complex fibrillar structure[23]
Summary
Structural proteins play critical roles in the food quality, especially texture properties, of sea cucumbers and their products. Comparative proteomics analysis revealed the spatial distribution heterogeneity of structural proteins in the sea cucumber body wall at a molecular scale. Sea cucumbers have been considered as nutritional foods, and demonstrated various biological activities such as gastric protection, anti-inflammation, anti-diabetes, and moisture-retention a ctivities[2,3,4,5]. Due to their biological activities and unique texture properties, sea cucumbers have attracted increasing research interest worldwide. The genome of sea Scientific Reports | (2020) 10:18744
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