Abstract

A stable niosome is prepared from Poly(ethylene glycol) [PEG] 6000/Tween 80/Span 80/H2O lamellar liquid crystal. The niosome structures and properties are studied by the methods of negative-staining transmission electron microscopy and small angle X-ray diffraction. A new calculating method is first put forward to obtain the microstructure and layer number of the niosome membrane. The membrane thickness and layer number of the niosome are 8–22 nm and 1–3.5 in PEG 6000/Tween 80/Span 80/H2O system.

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