Investigation of molecular interactions of streptomycin sulphate with aqueous L-aspartic acid through volumetric, ultrasonic and viscometric approach

Abstract

In the present study, physicochemical properties of streptomycin sulphate have been investigated in aqueous and mixed aqueous (0.0099, 0.0199, 0.0300) mol.kg−1 L-aspartic acid media at discrete temperatures (293.15 to 313.15 K) and experimental pressure, P = 101.3 kPa. The empirically measured physical properties such as density, velocity of sound, and viscosity have been utilized for the computation of several parameters such as apparent molar volume (Vϕ), limiting apparent molar volume (Vϕo), hydration number (nH), limiting apparent molar expansivity (Eϕo), apparent molar isentropic compression (Kϕ,s), limiting apparent molar isentropic compression (Kϕ,so), solvation number (Sn), Jones-Dole coefficients, and transfer parameters. Further, the cosphere overlap model has been employed for the acquaintance of varied probable intermolecular interactions operating in the prepared systems. The structure making tendency of the considered solute has been investigated via inference of 2c (Hepler’s constant) data. In addition, UV spectral analysis confirmed the persistence of effective dipole–dipole interactions in the prepared systems of study.