Investigation of Biological Activity, Open Porosity and Water Absorption of Ternary Polymeric Blend (Polymethylmethacrylate / Starch) used for Bone Scaffold

Sihama I Salih,Sally A Al-Saedi

doi:10.30539/iraqijvm.v42i2.303

Sihama I Salih, Sally A Al-Saedi

Open Access

https://doi.org/10.30539/iraqijvm.v42i2.303

Copy DOI

Abstract

In this study a fabrication of three groups of biological system for bone scaffold, which consist of first group samples (Acrylic bone cement: % X poly methyl meth acrylate ), second group samples (poly methyl meth acrylate: % X Acrylic bone cement), with selected weight percentages of second material are (5, 10,15 and 20 % wt.) and third group, (Acrylic bone cement: 15 % poly methyl meth acrylate : % X starch) with selected weight percentage ratios of starch are (2, 4 and 6 %wt.). In vitro biological activity and water absorption have been studied. The results clarified that the in vitro biological activity test showed that all fabricated samples have no biological influence on the gram positive bacteria Bacillus subtilis and gram negative bacteria Escherichia coli . The results show that the first group of polymer blend have low open porosity and water uptake capacity than a second group. The increasing in starch weight fraction for the third group led to increasing in open porosity and water absorption..

Highlights

Bones play an important role in our bodies, providing the ability to perform daily activities
Methyl meth acrylate (PMMA) is nonadhesive acrylic polymer that is widely used in orthopedics as bone cement for implants
The orthopedic use of Poly methyl meth acrylate (PMMA) cement was introduced in the early 1960s by Chanley and this was the first cement used for spine applications

Summary

Introduction

Bones play an important role in our bodies, providing the ability to perform daily activities. They are responsible for mineral storage and red blood cell production. Crop seeds and is produced by staple crops such as rice, corn, wheat, tapioca, and potato It is deposited in the chloroplast of plant cells as insoluble granules composed of α-amylose (normally 10–30%) and amylopectin(normally 70–90%), depending on its source. The aim of this study is to prepare three type of polymeric blends with PMMA as the base material which was used to improve antibacterial activity of biomaterials, firstly via blending different types of PMMA material, secondly via blending another type of chemically different polymers with optimum sample of the first groups as a tool for tailoring characteristics of the products with optimized material properties

Objectives

Methods

Discussion

Conclusion