Abstract
Investigating the potential of polymethoxy flavonoids (PMFs) as a means of halting the recruitment of osteoclasts in periodontal disease
Highlights
Further investigate the potential of polymethoxy flavonoids (PMFs) as a means of halting the recruitment of osteoclasts in periodontal disease
Verify the safety of sudachitin and work towards the development of a toothpaste containing sudachitin as a potential preventative measure against periodontal disease
My passion for my research arises from the simple questions: Why do people eat? and What is the meaning of eating? I believe in a well-managed diet
Summary
Further investigate the potential of polymethoxy flavonoids (PMFs) as a means of halting the recruitment of osteoclasts in periodontal disease. I devised this research when I learned that polymethoxy flavonoids (PMF) influence bone metabolism in other researchers’ papers It seemed this could provide an obvious benefit in my field of dentistry. We are investigating two PMFs of particular interest in Japan: nobiletin from the extremely common ponkan fruit and tangeretin from citrus depressa These PMFs have already been shown to inhibit bone loss reduction using periodontitis in a mouse model. Throughout my research career, discussion with collaborators has always been indispensable For this particular project, the discussions and consultations with Professor Yoshiyuki Hakeda of Meikai University School of Dentistry, Japan, were and are very important. The discussions and consultations with Professor Yoshiyuki Hakeda of Meikai University School of Dentistry, Japan, were and are very important He brings expertise in molecular biology and has taught me how to think about and process problems in my work.
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