Abstract

Post-traumatic stress disorder (PTSD) can present with an array of debilitating symptoms, including psychotic features. The limbic circuit has been largely implicated in the pathology of PTSD, though studies remain inconsistent, with only some results showing reductions in limbic volumes in patients with PTSD. In addition, no study has investigated the association between psychotic symptoms and brain macro- and microstructure in PTSD. The goal of the present study is to compare the macro- and microstructure of the limbic circuit between patients with PTSD, patients with PTSD and psychotic symptoms, and healthy individuals.

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