Abstract
A 37-year-old woman, with no history of diseases or medical treatment, presented with an asymptomatic nonulcerated lesion, at the lower posterior gingiva. The patient had periodontitis with periodical control and the intraoral exam showed a single, hardened nodule measuring 1 × 0.5 cm, with a smooth surface and sessile base, surrounding the interproximal distal space between the first and second left lower molars. Radiographically, there was no evidence of bone compromise. Pigmentation was only seen on the lingual area. An incisional biopsy was made, providing the diagnosis of melanoma with immunohistochemical positive reaction for HMB-45 and S-100. Chest radiograph and computer tomography (CT) scan of the cervical area was required to rule out any metastatic lesion; the results were negative. The patient underwent a mandibular and neck surgery showing 1 positive lymph node out of 37 sentinel lymph nodes. She received oncologic treatment with no recurrence after 3 years.
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