Abstract
An 81-year-old white man diagnosed with myelofibrosis was referred by his hematologist to the hospital dentistry service for evaluation of a gingival bleeding nodule. The patient was symptomatic and did not exhibit facial asymmetry. An erythematous, smooth surfaced, firm, sessile, nodular lesion, measuring 3 × 1 cm, localized on the vestibular gingiva between first and second maxillary right premolars was observed. There was bone loss and significant tooth mobility, and extraction of premolars and the associated nodule was performed. Microscopic analysis revealed sheets of mature and immature myeloid cells positive for CD68, Ki-67 (50%), and myeloperoxidase. A diagnosis of granulocytic sarcoma was made. The patient underwent a close follow-up, and no evidence of the systemic or local recurrence was observed. Support: FAPEMIG.
Published Version
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