Abstract

The aim of this study was to analyze the techniques for intraocular lens (IOL) implantation in patients with coloboma of the iris. A retrospective cohort study was used to analyze the degree of iris coloboma and the characteristics of the crystalline lens in 56 patients with iris coloboma. The patients with a lesser degree of coloboma of the iris and an intact lens capsule were treated by iris suture and IOL implantation into the posterior chamber. Patients with an iris coloboma confined to one quadrant, severe iris atrophy and significant lens capsule coloboma were treated with an annular suture at the edge of the pupil and IOL implantation into the anterior chamber. Patients with a greater degree of iris coloboma and an intact lens capsule were treated with an artificial iris and IOL implantation. The patients were followed up for between five months and five years after surgery. Data relating to vision, photophobia, IOL location, postoperative complications and treatment were also obtained at follow-up. The vision of the patients was improved to varying degrees following the surgery, with the exception of those with amblyopia or serious corneal scars. The photophobia of the patients had also improved. The patients’ levels of satisfaction and comfort were deemed to be satisfactory. Early postoperative complications included hyphema, increased intraocular pressure and uveitis. However, serious complications such as corneal decompensation and IOL dislocation were not observed. Various techniques for IOL implantation were selected based on the degree of iris and lens capsule coloboma; these techniques were capable of improving the vision and photophobia of the patients.

Highlights

  • The iris has important physiological functions with regard to regulating the amount of light that enters the eyes, increasing focal depth and decreasing eyeball aberrations [1]

  • Researchers have attempted several different surgical techniques to solve the problems associated with intraocular lens (IOL) implantation and to improve the photophobic conditions of patients with iris coloboma

  • When the extent of the iris coloboma is small, it is possible to directly suture the existing iris and reconstruct the pupils. This surgical technique was applied to patients with an iris coloboma of small range, and whose remaining iris was capable of being sutured

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Summary

Introduction

The iris has important physiological functions with regard to regulating the amount of light that enters the eyes, increasing focal depth and decreasing eyeball aberrations [1]. Trauma, surgery, the integrity of the iris is damaged or missing and normal morphology and size of pupil are damaged, referred to as the ‘iris defect’. These patients present with cataracts and crystalline lens dislocation [3,4]. Various surgical techniques may be used to conduct IOL implantation when patients exhibit with iris coloboma and cataracts [5,6]. A review of patients treated with various surgical techniques based on different iris coloboma and crystalline lens anomalies was carried out, and the results of the various treatments are reported

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