Abstract

Although many new and helpful treatments for dry eye disease have been developed, there remains a subset of patients who continue to look for easier or more effective treatments. A consecutive group of 28 moderate to severe dissatisfied dry eye patients in one practice were surveyed after initial exposure to and trial with a novel intranasal neurostimulation technique. Results were overall positive. Seventy-one percent had a favorable impression. Average rating on 1-10 scale was 6.92. Twenty-five percent purchased the device immediately despite no insurance coverage. Of those who did not buy, 100% said they would consider purchase later. Time and experience will show how valuable this new technology is and how it fits in the dry eye armamentarium.

Highlights

  • Despite many treatment advances in recent years, dry eye disease remains a conundrum for both doctors and patients

  • FDA approval for True Tear was granted in April, 2017, “to provide a temporary increase in tear production during neurostimulation in adult patients.”

  • All devicerelated events were mild, including nasal pain, discomfort or burning (10.3%) transient electrical discomfort (5.2%), and nosebleed (5.2%) [1]

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Summary

Introduction

Despite many treatment advances in recent years, dry eye disease remains a conundrum for both doctors and patients. An innovative biotech team in the Silicon Valley (Oculeve) produced a minimally invasive intranasal neurostimulation device for treating dry eye. FDA approval for True Tear was granted in April, 2017, “to provide a temporary increase in tear production during neurostimulation in adult patients.”. Neurostimulation for medical benefit is a concept at least several decades old. For years these techniques have benefited patients with multiple conditions such as chronic pain, post-herpetic neuralgia, complex migraines, and peripheral neuropathy. Patients with Parkinson’s disease [3], intractable epilepsy [4], and even obstructive sleep apnea [5], have benefited from neurostimulation

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