Abstract
Tissue engineering has revolutionized the medical field by giving us the hope of generating alternative human tissues that could replace diseased ones. On this front, the generation of tissue-engineered neo-intestine in animal models has been a great endeavor with the ultimate goal of replacing the diseased gut or to treat short gut syndrome. Although this field and the generated neo-intestine are still in their infancy, this idea is so attractive that it has fascinated all medical personnel including gastroenterologists and gastrointestinal surgeons. We herein introduce the salient features of a tissue-engineered intestine, the hopes associated with it, and the few practical constraints in developing a "mature" human tissue-engineered intestine, which would be sufficient to treat short gut syndrome.
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